Molecular biology

Definition

Molecular Biology is the field of biology that studies the composition, structure and interactions of cellular molecules – such as nucleic acids and proteins – that carry out the biological processes essential for the cell’s functions and maintenance.

Featured

Latest Research and Reviews

  • Research |

    CYREN is a direct inhibitor of classical non-homologous end joining that promotes error-free repair by homologous recombination during the S and G2 phases of the cell cycle.

    • Nausica Arnoult
    • , Adriana Correia
    • , Jiao Ma
    • , Anna Merlo
    • , Sara Garcia-Gomez
    • , Marija Maric
    • , Marco Tognetti
    • , Christopher W. Benner
    • , Simon J. Boulton
    • , Alan Saghatelian
    •  & Jan Karlseder
  • Research |

    Analysis of global remethylation in mouse embryos at several developmental stages identifies an epigenetic landscape that partitions extraembryonic tissues within the embryo and resembles a frequent, global departure in genome regulation in human cancers.

    • Zachary D. Smith
    • , Jiantao Shi
    • , Hongcang Gu
    • , Julie Donaghey
    • , Kendell Clement
    • , Davide Cacchiarelli
    • , Andreas Gnirke
    • , Franziska Michor
    •  & Alexander Meissner
  • Research |

    Genome editing in human zygotes shows that OCT4 is required for normal development at an earlier stage in humans than in mice.

    • Norah M. E. Fogarty
    • , Afshan McCarthy
    • , Kirsten E. Snijders
    • , Benjamin E. Powell
    • , Nada Kubikova
    • , Paul Blakeley
    • , Rebecca Lea
    • , Kay Elder
    • , Sissy E. Wamaitha
    • , Daesik Kim
    • , Valdone Maciulyte
    • , Jens Kleinjung
    • , Jin-Soo Kim
    • , Dagan Wells
    • , Ludovic Vallier
    • , Alessandro Bertero
    • , James M. A. Turner
    •  & Kathy K. Niakan
  • Research |

    A novel quantitative approach to identify intact glycopeptides from comparative proteomic data sets, allowing inference of complex glycan structures and direct mapping of them to sites within the associated proteins at the proteome scale.

    • Johannes Stadlmann
    • , Jasmin Taubenschmid
    • , Daniel Wenzel
    • , Anna Gattinger
    • , Gerhard Dürnberger
    • , Frederico Dusberger
    • , Ulrich Elling
    • , Lukas Mach
    • , Karl Mechtler
    •  & Josef M. Penninger

News and Comment