Cell biology

Definition

Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. Research in cell biology uses microscopic and molecular tools and examines all cell types, from unicellular organisms such as protozoa to the specialised cells that consitutute multicellular organisms.

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Latest Research and Reviews

  • Research |

    The growth of adult and paediatric brain tumours depends on a microenvironmental signalling pathway involving the activity-regulated secretion of neuroligin-3 (NLGN3) from normal neurons and oligodendrocyte precursor cells, highlighting the potential of NLGN3 as a therapeutic target.

    • Humsa S. Venkatesh
    • , Lydia T. Tam
    • , Pamelyn J. Woo
    • , James Lennon
    • , Surya Nagaraja
    • , Shawn M. Gillespie
    • , Jing Ni
    • , Damien Y. Duveau
    • , Patrick J. Morris
    • , Jean J. Zhao
    • , Craig J. Thomas
    •  & Michelle Monje
  • Research |

    CYREN is a direct inhibitor of classical non-homologous end joining that promotes error-free repair by homologous recombination during the S and G2 phases of the cell cycle.

    • Nausica Arnoult
    • , Adriana Correia
    • , Jiao Ma
    • , Anna Merlo
    • , Sara Garcia-Gomez
    • , Marija Maric
    • , Marco Tognetti
    • , Christopher W. Benner
    • , Simon J. Boulton
    • , Alan Saghatelian
    •  & Jan Karlseder
  • Research |

    A novel quantitative approach to identify intact glycopeptides from comparative proteomic data sets, allowing inference of complex glycan structures and direct mapping of them to sites within the associated proteins at the proteome scale.

    • Johannes Stadlmann
    • , Jasmin Taubenschmid
    • , Daniel Wenzel
    • , Anna Gattinger
    • , Gerhard Dürnberger
    • , Frederico Dusberger
    • , Ulrich Elling
    • , Lukas Mach
    • , Karl Mechtler
    •  & Josef M. Penninger
  • Research | | open

    Protrusive cellular structures contain a heterogeneous density of actin, but whether this influences motility is not known. Using an in vitro system and modelling, here the authors show that local actin monomer depletion and network architecture can tune the rate of network growth to impose steering during motility.

    • Rajaa Boujemaa-Paterski
    • , Cristian Suarez
    • , Tobias Klar
    • , Jie Zhu
    • , Christophe Guérin
    • , Alex Mogilner
    • , Manuel Théry
    •  & Laurent Blanchoin
  • Research | | open

    Inhibition of cell division maintains genome integrity in response to DNA damage. Here Chen et al. propose that DNA damage causes cell cycle arrest in the Arabidopsis root via Rep-MYB transcription factor-mediated repression of G2/M-specific gene expression in response to reduced cyclin-dependent kinase activity.

    • Poyu Chen
    • , Hirotomo Takatsuka
    • , Naoki Takahashi
    • , Rie Kurata
    • , Yoichiro Fukao
    • , Kosuke Kobayashi
    • , Masaki Ito
    •  & Masaaki Umeda

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